What is Lyrica / Pregabalin?

Pregabalin (known also as Lyrica) is an anti-epileptic medication, also called "anti-convulsant". It's used for neuropathic pain, as an adjunct therapy for seizures, with / without secondary generalization in adults. Pregabalin affects brain cells that send pain signals across the nervous system by changing their chemical composition.

Pregabalin is sold by Pfizer under the trade name Lyrica.

In 2007, Pregabalin was the first medication approved by the U.S. Food and Drug Administration specifically for fibromyalgia treatment. In December 2004 Pregabalin was approved by U.S. Food and Drug Administration (FDA) for use in treating epilepsy, diabetic neuropathy pain and post-herpetic neuralgia.

Pregabalin was developed by a medicinal chemist named Richard Bruce Silverman, at Northwestern University, United States, and was approved in 2004 in the European Union.

Lyrica is supplied as imprinted hard-shell capsules (25, 50, 75, 100, 150, 200, 225, and 300 mg of Pregabalin). The usage is oral. Pregabalin is a white crystalline solid, freely soluble in water and in both basic and acidic solutions.